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๐Ÿ“ˆ๐Ÿš€ Innovation Timelines

๐Ÿ’ป Information Technology - Innovation Timelineโ€‹

YearInnovationFeaturesInnovator
1450Printer๐Ÿ–จ๏ธ Movable metal type, oil-based ink, mass production of booksJohannes Gutenberg
1870TypewriterโŒจ๏ธ Mechanical keyboard, direct imprint of type on paper, faster and more legible writingChristopher Latham Sholes, E. Remington & Son
1928Data Processor๐Ÿ“„ IBM punch cards for data storage and processing; based on Jacquard textile machinesIBM
1936Computation Model๐Ÿ’ญ Theoretical computation model, Turing Machine testAlan Turing
1947Transistorโšก Revolutionized electronics; replaced vacuum tubes, enabling miniaturizationJohn Bardeen, Walter Brattain, William Shockley
1950Turing Test๐Ÿค– Test for human-like Intelligence of machines & decryptionAlan Turing
1957Perceptron๐Ÿ”— First single-layer neural networkFrank Rosenblatt
1960ELIZA Chatbot๐Ÿ’ฌ First chatbot programJoseph Weizenbaum
1962Sensorama VR๐Ÿฅฝ First VR machine with multi-sensory experienceMorton Heilig
1969ARPANET๐ŸŒ First computer network, TCP/IP, FTPDARPA
1968Intel๐Ÿ’พ Silicon microprocessor, Moore's Law (exponential growth of transistor density)Robert Noyce, Gordon Moore, Andy Grove
1972Email๐Ÿ“ง Computer-to-computer messaging system with @ SymbolRay Tomlinson
1979Usenet/BBS๐Ÿ–ง Local dial-up communities, message boards, file sharing, no central authorityWard Christensen, Tom Truscott, Jim Ellis
1981First 3D Printer Concept๐Ÿ–จ๏ธ Layer-by-layer photosensitive resin printingHideo Kodama
1983Domain Name System (DNS)๐Ÿ”— .com, .gov, .edu web addressing systemPaul Mockapetris
1986Backpropagationโšก Neural network training algorithm breakthroughRumelhart, Hinton & Williams
1987HyperCard๐Ÿ—‚๏ธ Stack-based hypertext system, cards with text/images/buttons, scripting (HyperTalk)Bill Atkinson (Apple)
1989World Wide Web๐Ÿ•ธ๏ธ HTML, HTTP, URL, Open source proposalTim Berners-Lee (CERN)
1993Web Browser๐ŸŒ Mosaic then Netscape, user-friendly browser with graphicsMarc Andreessen, Jim Clark
1994Amazon๐Ÿ›’ Online auction and marketplace platformJeff Bezos
1995Internet Explorer๐ŸŒ Microsoft's entry into browser marketMicrosoft
1997IBM Deep Blueโ™Ÿ๏ธ AI defeats world chess championIBM
1997Netflix๐Ÿ“€ DVD-by-mail rental serviceReed Hastings & Marc Randolph
1998Google Search๐Ÿ”Ž Became leading search engineLarry Page & Sergey Brin
1999Napster๐ŸŽต Peer-to-peer file sharing (music)Sean Parker, Shawn Fanning
2000Pandora๐ŸŽถ Internet radio and music streamingTim Westergren
2003LinkedIn๐Ÿ’ผ Professional networking platformReid Hoffman
2003MySpace๐Ÿ‘ฅ Early social media platformTom Anderson & Chris DeWolfe
2004Facebook๐Ÿ“˜ Social networking for universitiesMark Zuckerberg
2004Firefox๐ŸฆŠ Open-source browser with security featuresMozilla Foundation
2004Boston Dynamics BigDog๐Ÿ• Quadruped military support robotBoston Dynamics
2005YouTube๐Ÿ“บ Video sharing platformChad Hurley, Steve Chen & Jawed Karim
2005Android๐Ÿค– Mobile operating system development starts (acquired by Google)Andy Rubin
2002AWSโ˜๏ธ Launch of Cloud Computing infrastructure, S3 storage and EC2 computeJeff Bezos, Andy Jassy, Amazon
2006Twitter๐Ÿฆ Microblogging and social media platform (renamed came X)Jack Dorsey, Biz Stone & Evan Williams
2007iPhone๐Ÿ“ฑ Revolutionary touchscreen smartphoneSteve Jobs (Apple)
2007Android Beta๐Ÿ“ฑ First mobile OS releaseGoogle
2008Bitcoin & Blockchainโ‚ฟ First cryptocurrency and distributed ledgerAnonymous
2008Google Chrome๐ŸŒˆ Fast browser with V8 engine and multi-process architectureGoogle
2009WhatsApp๐Ÿ’š Cross-platform mobile messagingBrian Acton & Jan Koum
2010Instagram๐Ÿ“ธ Photo sharing with filtersKevin Systrom & Mike Krieger
2011IBM Watson๐Ÿง  AI wins at Jeopardy! game showIBM
2011Snapchat๐Ÿ‘ป Disappearing personal messagingEvan Spiegel & Bobby Murphy
2012AlexNet๐ŸŽฏ Deep learning breakthrough in image recognitionAlex Krizhevsky, Ilya Sutskever, Geoffrey Hinton
2012Oculus Kickstarter๐Ÿฅฝ VR headset crowdfunding campaignPalmer Luckey
2013Boston Dynamics Atlas๐Ÿค– Bipedal humanoid robot for search and rescueBoston Dynamics
2014Generative Adversarial Networks๐ŸŽญ Generative AI modelingIan Goodfellow
2016Oculus Rift๐Ÿฅฝ First major consumer VR headsetPalmer Luckey (Oculus/Meta)
2016TikTok๐ŸŽต Short-form algorithm-driven video platformByteDance
2017Transformer Architecture๐Ÿ”„ Attention mechanism revolutionizing NLPGoogle Research
2019Meta Quest๐Ÿฅฝ Standalone VR headset with hand trackingMeta (formerly Facebook)
2020GPT-3๐Ÿง  Large language model with 175 billion parametersOpenAI
2020Boston Dynamics Commercial Robot๐Ÿ• First commercial robot for industrial useBoston Dynamics
2022ChatGPT๐Ÿ’ฌ Conversational AI accessible to general publicOpenAI
2022Perplexity๐Ÿ” AI-powered search engine with conversational interfaceAravind Srinivas, Denis Yarats
2023GPT-4๐Ÿค– Multimodal AI with enhanced reasoning capabilitiesOpenAI
2024Brain interface trial๐Ÿง  Trials of brain implants enabling computer control via thought, restoring vision/limb controlElon Musk, Neuralink

๐Ÿ› ๏ธ Programming Tools - Innovation Timelineโ€‹

YearInnovationFeaturesInnovator
1957FORTRANScientific computing, mathematical operationsJohn Backus (IBM)
1959LISPAI research, symbolic computationJohn McCarthy
1969UnixMulti-user, portable operating systemKen Thompson & Dennis Ritchie
1970SQLStructured query language, relational DBIBM (System R)
1972CSystem programming, portable codeDennis Ritchie (Bell Labs)
1973TCP/IPInternet protocol suite, packet switchingVint Cerf & Bob Kahn
1984DNSDomain name resolution, hierarchical namingPaul Mockapetris
1990HTTPHTTP, HTML, URLs, WWW, client-serverTim Berners-Lee
1991LinuxOpen-source Unix-like systemLinus Torvalds
1991PythonReadable, simple language for machine learningGuido van Rossum
1994HTMLMarkup language, document structureTim Berners-Lee
1995JavaScriptClient-side scripting, dynamic contentBrendan Eich (Netscape)
1996CSSStylesheet language, presentation controlHรฅkon Wium Lie
2000RESTArchitectural style, stateless communicationRoy Fielding
2005GitDistributed version control, branchingLinus Torvalds
2006Amazon EC2Virtual computing, elastic cloudAmazon
2006jQueryDOM manipulation, cross-browser compatibilityJohn Resig
2007iOSMobile operating system, touch interfaceApple
2008GitHubGit hosting, social coding platformGitHub Inc.
2008AndroidOpen-source mobile OS, Java-basedGoogle
2009Node.jsServer-side JavaScript, event-drivenRyan Dahl
2012TypeScriptTyped JavaScript, large-scale developmentMicrosoft
2013DockerApplication containerization, portabilityDocker Inc.
2013ReactComponent-based UI, virtual DOMFacebook
2014Vue.jsProgressive framework, reactive dataEvan You
2015TensorFlowMachine learning platform, neural networksGoogle
2016Next.jsReact framework, server-side rendering, file-based routingGuillermo Rauch (Vercel)
2016SvelteCompiler-based framework, reactive UI, minimal runtimeRich Harris
2016PyTorchDynamic neural networks, research-friendlyFacebook
2018WebAssemblyBinary instruction format, near-native performanceW3C
2021CopilotAI code completion, pair programmingGitHub/OpenAI
2022ChatGPTConversational AI, code generationOpenAI
2023BunNode replacement, JavaScript runtime, bundlerJarred Sumner
2023ClaudeAdvanced AI assistant, reasoning capabilitiesAnthropic
2024GeminiMultimodal AI model, text and image processingGoogle

โœ๏ธ Text Editors - Innovation Timelineโ€‹

YearInnovationFeaturesInnovator
1962TECO, EDEarly line editors; command-based editingMIT, Bell Labs
1973Xerox AltoFirst GUI, mouse support, WYSIWYG editingXerox PARC
1976vi / VimModal editing; efficient keyboard navigationBill Joy (vi), Bram Moolenaar (Vim)
1978WordStarBlock editing, search/replace, page layoutMicroPro International
1983Microsoft WordWYSIWYG, mouse support, style sheets, spell-check, real-time collaboration (later)Microsoft
1999GNU NanoSimple command-line interface, syntax highlighting, undo/redoGNU Project
2003Notepad++Tabbed editing, syntax highlighting, plugin systemDon Ho
2004TinyMCE, CKEditorWeb-based WYSIWYG, plugin architecture, CMS integrationMoxiecode (TinyMCE), CKSource (CKEditor)
2006Google DocsReal-time cloud collaboration, revision history, commenting, web-based editingGoogle
2008Sublime TextMulti-selection, command palette, GPU rendering, goto anythingSublime HQ
2010CodeMirrorWeb-based code editing, 100+ language support, theming systemMarijn Haverbeke
2015VS Code/MonacoIntelliSense, web-based Monaco, Git integration, extensions marketplace, local file historyMicrosoft
2018Editor.jsBlock-based editing, clean JSON output, API extensibility, open sourceCodeX Team
2023CursorAI-powered code completion, pair programming, context-aware suggestionsAnysphere

๐Ÿ—๏ธ Materials & Energy - Innovation Timelineโ€‹

YearInnovationFeaturesInnovator
2500 BCEBronzeFirst metal alloy combining copper and tin; harder and more durable than pure copper; enabled advanced tools, weapons, and artAncient cultures
200 BCERoman ConcreteUsed volcanic ash (pozzolana) with lime; could set underwater; created durable structures lasting millenniaRoman Engineers/Vitruvius
105PaperMade from tree bark, hemp, old rags, and fishnets; lightweight, durable, inexpensive writing surface; revolutionized information storageCai Lun
850GunpowderMixture of sulfur, charcoal, and saltpeter; originally seeking elixir of life; revolutionized warfare and miningChinese Alchemists
1440Printing PressMovable type, oil-based ink, screw press mechanism; enabled mass production of books and spread of knowledgeJohannes Gutenberg
1769Steam Engine (Improved)Separate condenser design; dramatically improved efficiency over Newcomen engine; powered Industrial RevolutionJames Watt
1856Bessemer ProcessAir blown through molten iron to remove impurities; mass production of steel; revolutionized construction and industryHenry Bessemer
1859Oil Well DrillingCast iron pipe drilling method; reached oil at 69.5 feet depth; launched modern petroleum industryEdwin Drake
1876Internal Combustion EngineFour-stroke cycle (intake, compression, power, exhaust); 20-30% efficiency; foundation for automobilesNikolaus Otto
1879Incandescent Light BulbCarbon filament in vacuum bulb; 13+ hour burn time; enabled widespread electric lighting systemsThomas Edison
1886Hall-Hรฉroult ProcessElectrolytic aluminum production using cryolite; made aluminum widely available and affordableCharles Hall & Paul Hรฉroult
1891Wind Turbine (Electric)First electricity-generating windmill; stored energy as hydrogen; constant power with Katrostat regulationPoul la Cour
1907BakeliteFirst fully synthetic plastic from phenol and formaldehyde; heat-resistant, non-conductive; 'Material of a Thousand Uses'Leo Baekeland
1935NylonFirst wholly synthetic fabric; stronger than silk; revolutionized textiles and polymer scienceWallace Carothers
1942Nuclear ReactorFirst controlled nuclear chain reaction in Chicago Pile-1; foundation for nuclear power generationEnrico Fermi
1947TransistorGermanium point-contact device; amplified electrical signals 100x; enabled modern electronics revolutionJohn Bardeen & Walter Brattain
1954Solar CellSilicon semiconductor converts light to electricity; 6% efficiency; foundation of solar power industryDaryl Chapin, Calvin Fuller, Gerald Pearson
1958Carbon FiberHeating acrylic fibers creates lightweight, strong material; 5x stronger than steel; revolutionized aerospaceRoger Bacon
1962LEDFirst visible LED using gallium arsenide phosphide; red light emission; transformed lighting and displaysNick Holonyak Jr.
1980Lithium-ion BatteryLithium cobalt oxide cathode; high energy density, rechargeable; enabled portable electronics and electric vehiclesJohn Goodenough

๐Ÿš— Transportation - Innovation Timelineโ€‹

YearInnovationInnovatorFeatures
3500 BCEWheelSumeriansFirst rotating axle, wooden disc, horse cart
1769Steam-Powered VehicleNicolas-Joseph CugnotFirst self-propelled road vehicle using steam engine
1804Steam LocomotiveRichard TrevithickFirst locomotive to haul wagons and passengers on rails
1825RailwayGeorge StephensonFirst public steam railway; enabled mass passenger and freight movement
1885Petroleum Reitwagen (Motorcycle)Gottlieb Daimler, Wilhelm MaybachFirst internal combustion motorcycle
1886Benz Patent-MotorwagenKarl BenzFirst true automobile; three wheels, internal combustion engine
1888Flocken ElektrowagenAndreas FlockenFirst real electric car; battery-powered
1894ElectrobatPedro Salom, Henry G. MorrisEarly electric car; 25-mile range; used as taxis in New York
1900Lohner-Porsche HybridFerdinand PorscheFirst hybrid car; combined electric motor and gasoline engine
1908Ford Model THenry FordFirst mass-produced, affordable car for the public
1913Moving Assembly LineHenry FordReduced car production time from 728 to 93 minutes
1921Four-Wheel BrakesMalcolm Loughead (Lockheed)Improved vehicle stopping power and safety
1929Car RadioPaul Galvin (Galvin Manufacturing)First commercial car radio, introduced as "Motorola"
1941Jet Engine (First Jet-Powered Aircraft)Frank Whittle, Hans von OhainEnabled much faster, higher-altitude air travel; led to mass commercial jet airliners in the 1950s
1956โ€“1970Interstate Highway SystemU.S. Federal GovernmentTransformed road transport; enabled high-speed, long-distance travel and suburban growth
1969Moon LandingNASAFirst successful crewed lunar landing (Apollo 11); advanced rocket technology and guidance systems
1959Three-Point SeatbeltNils Bohlin (Volvo)Major safety innovation; became standard worldwide
1971Anti-lock Braking System (ABS)BoschPrevents wheel lock during braking; enhances control
1997Toyota PriusToyota Motor CorporationFirst mass-produced hybrid car; gasoline engine + electric motor
1999Adaptive Cruise ControlMercedes-BenzRadar-based system to maintain safe following distance
2002Backup CameraInfiniti (Nissan)First production car with rear-view backup camera
2009Google Self-Driving Car ProjectGoogle (Sebastian Thrun, et al.)First large-scale autonomous vehicle development
2015Tesla Autopilot 1.0Tesla, Inc. (Elon Musk)Semi-autonomous driving: Traffic Aware Cruise Control, Autosteer, Auto Lane Change
2020Waymo Driverless Taxi ServiceWaymo (Alphabet Inc.)First commercial autonomous ride-hailing service without safety drivers

๐Ÿงฌ Science - Innovation Timelineโ€‹

YearDiscovery๐Ÿ”ฌ Impact & SignificancePioneer(s)
~300 BCEEuclidean Geometry๐Ÿ“ Mathematical foundation of physics; space descriptionEuclid
1687Laws of Motion & Gravity๐ŸŒ Universal laws governing all motion; celestial mechanicsIsaac Newton
1800Electric Currentโšก Foundation of electrical technology; voltaic pileAlessandro Volta
1831Electromagnetic Induction๐Ÿ”Œ Basis for generators, motors, transformersMichael Faraday
1864Electromagnetic Theory๐Ÿ“ก Light as electromagnetic waves; unified E&MJames Clerk Maxwell
1895X-rays๐Ÿฉป Medical imaging; atomic structure studiesWilhelm Rรถntgen
1896Radioactivityโ˜ข๏ธ Nuclear physics; atomic energyHenri Becquerel
1897Electronโš›๏ธ First subatomic particle; atomic structureJ.J. Thomson
1900Quantum Theory๐ŸŒˆ Energy quantization; birth of quantum mechanicsMax Planck
1905Special Relativityโฑ๏ธ Space-time unity; E=mcยฒ; speed of light limitAlbert Einstein
1911Atomic Nucleus๐ŸŽฏ Nuclear model of atom; nuclear physicsErnest Rutherford
1913Bohr Model๐Ÿ”„ Quantized atomic orbits; spectroscopyNiels Bohr
1915General Relativity๐ŸŒŒ Gravity as curved spacetime; cosmologyAlbert Einstein
1925-27Quantum Mechanics๐ŸŽฒ Wave-particle duality; uncertainty principleHeisenberg, Schrรถdinger, Bohr
1927Big Bang Theory๐Ÿ’ฅ Origin and expansion of universeGeorges Lemaรฎtre
1929Expanding Universe๐Ÿ”ญ Galaxies receding; cosmic expansion confirmedEdwin Hubble
1932Neutronโšช Nuclear structure; fission possibilityJames Chadwick
1932Antimatterโž•โž– Positron discovery; matter-antimatter symmetryCarl David Anderson
1938Nuclear Fissionโš›๏ธ๐Ÿ’ฅ Nuclear power; atomic weaponsHahn, Meitner, Strassmann
1948Quantum Electrodynamics๐Ÿ”€ Quantum field theory; most accurate theoryFeynman, Tomonaga, Schwinger
1956Neutrino Detection๐Ÿ‘ป Ghostly particles; solar processesCowan & Reines
1964Quarks๐Ÿ”ด๐Ÿ”ต Building blocks of protons/neutronsGell-Mann & Zweig
1965Cosmic Microwave Background๐Ÿ“ป Big Bang evidence; universe's baby picturePenzias & Wilson
1967Electroweak Unification๐Ÿ”— Two forces unified; Standard ModelWeinberg, Salam, Glashow
1970-73Standard Model๐Ÿงฉ Complete theory of particles and forcesVarious physicists
1974Hawking Radiation๐Ÿ•ณ๏ธ Black holes evaporate; quantum gravityStephen Hawking
1980Quantum Computing๐Ÿ’ป Quantum information processing proposedRichard Feynman
1995Bose-Einstein Condensateโ„๏ธ New state of matter; quantum effects visibleKetterle, Cornell, Wieman
1998Dark Energy๐ŸŒ‘ Accelerating universe expansionSupernova teams
2012Higgs Boson๐ŸŽพ Origin of mass; Standard Model completedCERN LHC teams
2015Gravitational Waves๐ŸŒŠ Spacetime ripples detected; new astronomyLIGO collaboration
2019Black Hole Image๐Ÿ“ธ First visual proof; event horizon confirmedEvent Horizon Telescope

๐Ÿงฌ Medicine - Innovation Timelineโ€‹

YearInnovationFeaturesInnovator
c.460-377 BCEHippocratic Medicineโš•๏ธ Systematic observation, Hippocratic Oath, clinical approachHippocrates
1543Human Anatomy๐Ÿ“– Detailed anatomical study; foundation of modern anatomyAndreas Vesalius
1590sCompound Microscope๐Ÿ”ฌ Magnification of specimens; enabled cellular discoveryHans & Zacharias Janssen
1628Blood Circulation๐Ÿ’“ Discovery of circulatory system; foundation of cardiologyWilliam Harvey
1665Cell Discovery๐Ÿ”ฌ First observation of cells; basis of cell theoryRobert Hooke
1683Bacteria Discovery๐Ÿฆ  First observation of microorganisms; microbiology foundationAnton van Leeuwenhoek
1796Vaccination๐Ÿ’‰ First vaccine using cowpox to prevent smallpoxEdward Jenner
1816Stethoscope๐Ÿฉบ First instrument for cardiac auscultationRenรฉ Laennec
1842Anesthesia๐Ÿ˜ด First surgical anesthesia using ether; painless surgeryCrawford Long
1846Public Anesthesia๐Ÿฅ First public demonstration of surgical anesthesiaWilliam Morton
1847Antiseptic Surgery๐Ÿงผ Hand washing reduces puerperal fever deathsIgnaz Semmelweis
1859Evolution Theory๐Ÿงฌ Natural selection; foundation of modern biologyCharles Darwin
1865Genetics Laws๐ŸŒฑ Laws of inheritance; foundation of geneticsGregor Mendel
1867Antiseptic Principle๐Ÿงฝ Carbolic acid antisepsis; reduced surgical infectionsJoseph Lister
1869Periodic Tableโš›๏ธ Chemical element organization; basis of chemistryDmitri Mendeleev
1882TB Bacillus Discovery๐Ÿ”ฌ Identification of tuberculosis pathogenRobert Koch
1895X-raysโ˜ข๏ธ Medical imaging; first internal body visualizationWilhelm Rรถntgen
1897Electron Discoveryโšก Fundamental particle discovery; physics foundationJ.J. Thomson
1901Blood Types๐Ÿฉธ ABO blood group system; safe blood transfusionsKarl Landsteiner
1903Electrocardiograph๐Ÿ’“ First ECG machine; heart electrical activity measurementWillem Einthoven
1905Special Relativity๐ŸŒŒ Time-space relationship; modern physics foundationAlbert Einstein
1928Penicillin๐Ÿ’Š First antibiotic; revolutionized infection treatmentAlexander Fleming
1929Insulin Treatment๐Ÿ’‰ Hormone therapy for diabetes; first protein drugFrederick Banting, Charles Best
1943Kidney Dialysis๐Ÿฅ First artificial kidney machine; renal replacement therapyWillem Kolff
1944Heart Surgery๐Ÿ’— First successful cardiac procedure with bypassAlfred Blalock, Helen Taussig
1951HeLa Cells๐Ÿงช First immortal human cell line; cancer research toolGeorge Gey, Henrietta Lacks
1953DNA Structure๐Ÿงฌ Double helix discovery; molecular biology foundationJames Watson, Francis Crick
1954Kidney Transplant๐Ÿซ˜ First successful organ transplantationJoseph Murray
1955Polio Vaccine๐Ÿ’‰ First effective polio prevention; mass vaccinationJonas Salk
1967Heart Transplant๐Ÿ’ First human heart transplantationChristiaan Barnard
1972CT Scan๐Ÿ–ฅ๏ธ Computer tomography; 3D medical imagingGodfrey Hounsfield
1973Recombinant DNA๐Ÿงฌ Genetic engineering technology; biotechnology birthStanley Cohen, Herbert Boyer
1975Monoclonal Antibodies๐Ÿ”ฌ Targeted therapy production; precision medicineCรฉsar Milstein, Georges Kรถhler
1978IVF Birth๐Ÿ‘ถ First test-tube baby; reproductive medicineRobert Edwards, Patrick Steptoe
1979MRI Imaging๐Ÿง  Magnetic resonance imaging; soft tissue visualizationPaul Lauterbur, Peter Mansfield
1982Artificial Heart๐Ÿค– First artificial heart implant; mechanical organRobert Jarvik
1985PCR Technology๐Ÿงฌ DNA amplification; molecular diagnostics revolutionKary Mullis
1990Gene Therapy๐Ÿงฌ First approved gene therapy for ADA deficiencyWilliam French Anderson
1996Cloning (Dolly)๐Ÿ‘ First cloned mammal; reproductive technologyIan Wilmut, Roslin Institute
2001Human Genome Project๐Ÿงฌ Complete human DNA sequence; personalized medicineInternational Human Genome Consortium
2003Face Transplant๐Ÿ‘ค First partial face transplantationJean-Michel Dubernard
2006HPV Vaccine๐Ÿ’‰ First cancer prevention vaccineIan Frazer
2007iPS Cells๐Ÿ”„ Induced pluripotent stem cells; regenerative medicineShinya Yamanaka
20103D Bioprinting๐Ÿ–จ๏ธ First bioprinted blood vessels; organ printingOrganovo
2012CRISPR Gene Editingโœ‚๏ธ Precise DNA editing tool; genetic disease treatmentJennifer Doudna, Emmanuelle Charpentier
2013Cancer Therapy๐Ÿ›ก๏ธ Engineered immune cells; cancer immunotherapyCarl June, University of Pennsylvania
2018CRISPR Babies๐Ÿ‘ถ First gene-edited human babies (controversial)He Jiankui
2020mRNA Vaccines๐Ÿ’‰ Rapid COVID-19 vaccine development; mRNA technologyBioNTech/Pfizer, Moderna
2021AI Drug Discovery๐Ÿค– AI-designed drugs enter clinical trials; computational medicineDeepMind, Multiple Pharma Companies
2023Base Editing๐Ÿ”ฌ Precise single-letter DNA editing; next-gen gene therapyDavid Liu, Broad Institute