๐๐ Innovation Timelines
๐ป Information Technology - Innovation Timelineโ
Year | Innovation | Features | Innovator |
---|---|---|---|
1450 | Printer | ๐จ๏ธ Movable metal type, oil-based ink, mass production of books | Johannes Gutenberg |
1870 | Typewriter | โจ๏ธ Mechanical keyboard, direct imprint of type on paper, faster and more legible writing | Christopher Latham Sholes, E. Remington & Son |
1928 | Data Processor | ๐ IBM punch cards for data storage and processing; based on Jacquard textile machines | IBM |
1936 | Computation Model | ๐ญ Theoretical computation model, Turing Machine test | Alan Turing |
1947 | Transistor | โก Revolutionized electronics; replaced vacuum tubes, enabling miniaturization | John Bardeen, Walter Brattain, William Shockley |
1950 | Turing Test | ๐ค Test for human-like Intelligence of machines & decryption | Alan Turing |
1957 | Perceptron | ๐ First single-layer neural network | Frank Rosenblatt |
1960 | ELIZA Chatbot | ๐ฌ First chatbot program | Joseph Weizenbaum |
1962 | Sensorama VR | ๐ฅฝ First VR machine with multi-sensory experience | Morton Heilig |
1969 | ARPANET | ๐ First computer network, TCP/IP, FTP | DARPA |
1968 | Intel | ๐พ Silicon microprocessor, Moore's Law (exponential growth of transistor density) | Robert Noyce, Gordon Moore, Andy Grove |
1972 | ๐ง Computer-to-computer messaging system with @ Symbol | Ray Tomlinson | |
1979 | Usenet/BBS | ๐ง Local dial-up communities, message boards, file sharing, no central authority | Ward Christensen, Tom Truscott, Jim Ellis |
1981 | First 3D Printer Concept | ๐จ๏ธ Layer-by-layer photosensitive resin printing | Hideo Kodama |
1983 | Domain Name System (DNS) | ๐ .com, .gov, .edu web addressing system | Paul Mockapetris |
1986 | Backpropagation | โก Neural network training algorithm breakthrough | Rumelhart, Hinton & Williams |
1987 | HyperCard | ๐๏ธ Stack-based hypertext system, cards with text/images/buttons, scripting (HyperTalk) | Bill Atkinson (Apple) |
1989 | World Wide Web | ๐ธ๏ธ HTML, HTTP, URL, Open source proposal | Tim Berners-Lee (CERN) |
1993 | Web Browser | ๐ Mosaic then Netscape, user-friendly browser with graphics | Marc Andreessen, Jim Clark |
1994 | Amazon | ๐ Online auction and marketplace platform | Jeff Bezos |
1995 | Internet Explorer | ๐ Microsoft's entry into browser market | Microsoft |
1997 | IBM Deep Blue | โ๏ธ AI defeats world chess champion | IBM |
1997 | Netflix | ๐ DVD-by-mail rental service | Reed Hastings & Marc Randolph |
1998 | Google Search | ๐ Became leading search engine | Larry Page & Sergey Brin |
1999 | Napster | ๐ต Peer-to-peer file sharing (music) | Sean Parker, Shawn Fanning |
2000 | Pandora | ๐ถ Internet radio and music streaming | Tim Westergren |
2003 | ๐ผ Professional networking platform | Reid Hoffman | |
2003 | MySpace | ๐ฅ Early social media platform | Tom Anderson & Chris DeWolfe |
2004 | ๐ Social networking for universities | Mark Zuckerberg | |
2004 | Firefox | ๐ฆ Open-source browser with security features | Mozilla Foundation |
2004 | Boston Dynamics BigDog | ๐ Quadruped military support robot | Boston Dynamics |
2005 | YouTube | ๐บ Video sharing platform | Chad Hurley, Steve Chen & Jawed Karim |
2005 | Android | ๐ค Mobile operating system development starts (acquired by Google) | Andy Rubin |
2002 | AWS | โ๏ธ Launch of Cloud Computing infrastructure, S3 storage and EC2 compute | Jeff Bezos, Andy Jassy, Amazon |
2006 | ๐ฆ Microblogging and social media platform (renamed came X) | Jack Dorsey, Biz Stone & Evan Williams | |
2007 | iPhone | ๐ฑ Revolutionary touchscreen smartphone | Steve Jobs (Apple) |
2007 | Android Beta | ๐ฑ First mobile OS release | |
2008 | Bitcoin & Blockchain | โฟ First cryptocurrency and distributed ledger | Anonymous |
2008 | Google Chrome | ๐ Fast browser with V8 engine and multi-process architecture | |
2009 | ๐ Cross-platform mobile messaging | Brian Acton & Jan Koum | |
2010 | ๐ธ Photo sharing with filters | Kevin Systrom & Mike Krieger | |
2011 | IBM Watson | ๐ง AI wins at Jeopardy! game show | IBM |
2011 | Snapchat | ๐ป Disappearing personal messaging | Evan Spiegel & Bobby Murphy |
2012 | AlexNet | ๐ฏ Deep learning breakthrough in image recognition | Alex Krizhevsky, Ilya Sutskever, Geoffrey Hinton |
2012 | Oculus Kickstarter | ๐ฅฝ VR headset crowdfunding campaign | Palmer Luckey |
2013 | Boston Dynamics Atlas | ๐ค Bipedal humanoid robot for search and rescue | Boston Dynamics |
2014 | Generative Adversarial Networks | ๐ญ Generative AI modeling | Ian Goodfellow |
2016 | Oculus Rift | ๐ฅฝ First major consumer VR headset | Palmer Luckey (Oculus/Meta) |
2016 | TikTok | ๐ต Short-form algorithm-driven video platform | ByteDance |
2017 | Transformer Architecture | ๐ Attention mechanism revolutionizing NLP | Google Research |
2019 | Meta Quest | ๐ฅฝ Standalone VR headset with hand tracking | Meta (formerly Facebook) |
2020 | GPT-3 | ๐ง Large language model with 175 billion parameters | OpenAI |
2020 | Boston Dynamics Commercial Robot | ๐ First commercial robot for industrial use | Boston Dynamics |
2022 | ChatGPT | ๐ฌ Conversational AI accessible to general public | OpenAI |
2022 | Perplexity | ๐ AI-powered search engine with conversational interface | Aravind Srinivas, Denis Yarats |
2023 | GPT-4 | ๐ค Multimodal AI with enhanced reasoning capabilities | OpenAI |
2024 | Brain interface trial | ๐ง Trials of brain implants enabling computer control via thought, restoring vision/limb control | Elon Musk, Neuralink |
๐ ๏ธ Programming Tools - Innovation Timelineโ
Year | Innovation | Features | Innovator |
---|---|---|---|
1957 | FORTRAN | Scientific computing, mathematical operations | John Backus (IBM) |
1959 | LISP | AI research, symbolic computation | John McCarthy |
1969 | Unix | Multi-user, portable operating system | Ken Thompson & Dennis Ritchie |
1970 | SQL | Structured query language, relational DB | IBM (System R) |
1972 | C | System programming, portable code | Dennis Ritchie (Bell Labs) |
1973 | TCP/IP | Internet protocol suite, packet switching | Vint Cerf & Bob Kahn |
1984 | DNS | Domain name resolution, hierarchical naming | Paul Mockapetris |
1990 | HTTP | HTTP, HTML, URLs, WWW, client-server | Tim Berners-Lee |
1991 | Linux | Open-source Unix-like system | Linus Torvalds |
1991 | Python | Readable, simple language for machine learning | Guido van Rossum |
1994 | HTML | Markup language, document structure | Tim Berners-Lee |
1995 | JavaScript | Client-side scripting, dynamic content | Brendan Eich (Netscape) |
1996 | CSS | Stylesheet language, presentation control | Hรฅkon Wium Lie |
2000 | REST | Architectural style, stateless communication | Roy Fielding |
2005 | Git | Distributed version control, branching | Linus Torvalds |
2006 | Amazon EC2 | Virtual computing, elastic cloud | Amazon |
2006 | jQuery | DOM manipulation, cross-browser compatibility | John Resig |
2007 | iOS | Mobile operating system, touch interface | Apple |
2008 | GitHub | Git hosting, social coding platform | GitHub Inc. |
2008 | Android | Open-source mobile OS, Java-based | |
2009 | Node.js | Server-side JavaScript, event-driven | Ryan Dahl |
2012 | TypeScript | Typed JavaScript, large-scale development | Microsoft |
2013 | Docker | Application containerization, portability | Docker Inc. |
2013 | React | Component-based UI, virtual DOM | |
2014 | Vue.js | Progressive framework, reactive data | Evan You |
2015 | TensorFlow | Machine learning platform, neural networks | |
2016 | Next.js | React framework, server-side rendering, file-based routing | Guillermo Rauch (Vercel) |
2016 | Svelte | Compiler-based framework, reactive UI, minimal runtime | Rich Harris |
2016 | PyTorch | Dynamic neural networks, research-friendly | |
2018 | WebAssembly | Binary instruction format, near-native performance | W3C |
2021 | Copilot | AI code completion, pair programming | GitHub/OpenAI |
2022 | ChatGPT | Conversational AI, code generation | OpenAI |
2023 | Bun | Node replacement, JavaScript runtime, bundler | Jarred Sumner |
2023 | Claude | Advanced AI assistant, reasoning capabilities | Anthropic |
2024 | Gemini | Multimodal AI model, text and image processing |
โ๏ธ Text Editors - Innovation Timelineโ
Year | Innovation | Features | Innovator |
---|---|---|---|
1962 | TECO, ED | Early line editors; command-based editing | MIT, Bell Labs |
1973 | Xerox Alto | First GUI, mouse support, WYSIWYG editing | Xerox PARC |
1976 | vi / Vim | Modal editing; efficient keyboard navigation | Bill Joy (vi), Bram Moolenaar (Vim) |
1978 | WordStar | Block editing, search/replace, page layout | MicroPro International |
1983 | Microsoft Word | WYSIWYG, mouse support, style sheets, spell-check, real-time collaboration (later) | Microsoft |
1999 | GNU Nano | Simple command-line interface, syntax highlighting, undo/redo | GNU Project |
2003 | Notepad++ | Tabbed editing, syntax highlighting, plugin system | Don Ho |
2004 | TinyMCE, CKEditor | Web-based WYSIWYG, plugin architecture, CMS integration | Moxiecode (TinyMCE), CKSource (CKEditor) |
2006 | Google Docs | Real-time cloud collaboration, revision history, commenting, web-based editing | |
2008 | Sublime Text | Multi-selection, command palette, GPU rendering, goto anything | Sublime HQ |
2010 | CodeMirror | Web-based code editing, 100+ language support, theming system | Marijn Haverbeke |
2015 | VS Code/Monaco | IntelliSense, web-based Monaco, Git integration, extensions marketplace, local file history | Microsoft |
2018 | Editor.js | Block-based editing, clean JSON output, API extensibility, open source | CodeX Team |
2023 | Cursor | AI-powered code completion, pair programming, context-aware suggestions | Anysphere |
๐๏ธ Materials & Energy - Innovation Timelineโ
Year | Innovation | Features | Innovator |
---|---|---|---|
2500 BCE | Bronze | First metal alloy combining copper and tin; harder and more durable than pure copper; enabled advanced tools, weapons, and art | Ancient cultures |
200 BCE | Roman Concrete | Used volcanic ash (pozzolana) with lime; could set underwater; created durable structures lasting millennia | Roman Engineers/Vitruvius |
105 | Paper | Made from tree bark, hemp, old rags, and fishnets; lightweight, durable, inexpensive writing surface; revolutionized information storage | Cai Lun |
850 | Gunpowder | Mixture of sulfur, charcoal, and saltpeter; originally seeking elixir of life; revolutionized warfare and mining | Chinese Alchemists |
1440 | Printing Press | Movable type, oil-based ink, screw press mechanism; enabled mass production of books and spread of knowledge | Johannes Gutenberg |
1769 | Steam Engine (Improved) | Separate condenser design; dramatically improved efficiency over Newcomen engine; powered Industrial Revolution | James Watt |
1856 | Bessemer Process | Air blown through molten iron to remove impurities; mass production of steel; revolutionized construction and industry | Henry Bessemer |
1859 | Oil Well Drilling | Cast iron pipe drilling method; reached oil at 69.5 feet depth; launched modern petroleum industry | Edwin Drake |
1876 | Internal Combustion Engine | Four-stroke cycle (intake, compression, power, exhaust); 20-30% efficiency; foundation for automobiles | Nikolaus Otto |
1879 | Incandescent Light Bulb | Carbon filament in vacuum bulb; 13+ hour burn time; enabled widespread electric lighting systems | Thomas Edison |
1886 | Hall-Hรฉroult Process | Electrolytic aluminum production using cryolite; made aluminum widely available and affordable | Charles Hall & Paul Hรฉroult |
1891 | Wind Turbine (Electric) | First electricity-generating windmill; stored energy as hydrogen; constant power with Katrostat regulation | Poul la Cour |
1907 | Bakelite | First fully synthetic plastic from phenol and formaldehyde; heat-resistant, non-conductive; 'Material of a Thousand Uses' | Leo Baekeland |
1935 | Nylon | First wholly synthetic fabric; stronger than silk; revolutionized textiles and polymer science | Wallace Carothers |
1942 | Nuclear Reactor | First controlled nuclear chain reaction in Chicago Pile-1; foundation for nuclear power generation | Enrico Fermi |
1947 | Transistor | Germanium point-contact device; amplified electrical signals 100x; enabled modern electronics revolution | John Bardeen & Walter Brattain |
1954 | Solar Cell | Silicon semiconductor converts light to electricity; 6% efficiency; foundation of solar power industry | Daryl Chapin, Calvin Fuller, Gerald Pearson |
1958 | Carbon Fiber | Heating acrylic fibers creates lightweight, strong material; 5x stronger than steel; revolutionized aerospace | Roger Bacon |
1962 | LED | First visible LED using gallium arsenide phosphide; red light emission; transformed lighting and displays | Nick Holonyak Jr. |
1980 | Lithium-ion Battery | Lithium cobalt oxide cathode; high energy density, rechargeable; enabled portable electronics and electric vehicles | John Goodenough |
๐ Transportation - Innovation Timelineโ
Year | Innovation | Innovator | Features |
---|---|---|---|
3500 BCE | Wheel | Sumerians | First rotating axle, wooden disc, horse cart |
1769 | Steam-Powered Vehicle | Nicolas-Joseph Cugnot | First self-propelled road vehicle using steam engine |
1804 | Steam Locomotive | Richard Trevithick | First locomotive to haul wagons and passengers on rails |
1825 | Railway | George Stephenson | First public steam railway; enabled mass passenger and freight movement |
1885 | Petroleum Reitwagen (Motorcycle) | Gottlieb Daimler, Wilhelm Maybach | First internal combustion motorcycle |
1886 | Benz Patent-Motorwagen | Karl Benz | First true automobile; three wheels, internal combustion engine |
1888 | Flocken Elektrowagen | Andreas Flocken | First real electric car; battery-powered |
1894 | Electrobat | Pedro Salom, Henry G. Morris | Early electric car; 25-mile range; used as taxis in New York |
1900 | Lohner-Porsche Hybrid | Ferdinand Porsche | First hybrid car; combined electric motor and gasoline engine |
1908 | Ford Model T | Henry Ford | First mass-produced, affordable car for the public |
1913 | Moving Assembly Line | Henry Ford | Reduced car production time from 728 to 93 minutes |
1921 | Four-Wheel Brakes | Malcolm Loughead (Lockheed) | Improved vehicle stopping power and safety |
1929 | Car Radio | Paul Galvin (Galvin Manufacturing) | First commercial car radio, introduced as "Motorola" |
1941 | Jet Engine (First Jet-Powered Aircraft) | Frank Whittle, Hans von Ohain | Enabled much faster, higher-altitude air travel; led to mass commercial jet airliners in the 1950s |
1956โ1970 | Interstate Highway System | U.S. Federal Government | Transformed road transport; enabled high-speed, long-distance travel and suburban growth |
1969 | Moon Landing | NASA | First successful crewed lunar landing (Apollo 11); advanced rocket technology and guidance systems |
1959 | Three-Point Seatbelt | Nils Bohlin (Volvo) | Major safety innovation; became standard worldwide |
1971 | Anti-lock Braking System (ABS) | Bosch | Prevents wheel lock during braking; enhances control |
1997 | Toyota Prius | Toyota Motor Corporation | First mass-produced hybrid car; gasoline engine + electric motor |
1999 | Adaptive Cruise Control | Mercedes-Benz | Radar-based system to maintain safe following distance |
2002 | Backup Camera | Infiniti (Nissan) | First production car with rear-view backup camera |
2009 | Google Self-Driving Car Project | Google (Sebastian Thrun, et al.) | First large-scale autonomous vehicle development |
2015 | Tesla Autopilot 1.0 | Tesla, Inc. (Elon Musk) | Semi-autonomous driving: Traffic Aware Cruise Control, Autosteer, Auto Lane Change |
2020 | Waymo Driverless Taxi Service | Waymo (Alphabet Inc.) | First commercial autonomous ride-hailing service without safety drivers |
๐งฌ Science - Innovation Timelineโ
Year | Discovery | ๐ฌ Impact & Significance | Pioneer(s) |
---|---|---|---|
~300 BCE | Euclidean Geometry | ๐ Mathematical foundation of physics; space description | Euclid |
1687 | Laws of Motion & Gravity | ๐ Universal laws governing all motion; celestial mechanics | Isaac Newton |
1800 | Electric Current | โก Foundation of electrical technology; voltaic pile | Alessandro Volta |
1831 | Electromagnetic Induction | ๐ Basis for generators, motors, transformers | Michael Faraday |
1864 | Electromagnetic Theory | ๐ก Light as electromagnetic waves; unified E&M | James Clerk Maxwell |
1895 | X-rays | ๐ฉป Medical imaging; atomic structure studies | Wilhelm Rรถntgen |
1896 | Radioactivity | โข๏ธ Nuclear physics; atomic energy | Henri Becquerel |
1897 | Electron | โ๏ธ First subatomic particle; atomic structure | J.J. Thomson |
1900 | Quantum Theory | ๐ Energy quantization; birth of quantum mechanics | Max Planck |
1905 | Special Relativity | โฑ๏ธ Space-time unity; E=mcยฒ; speed of light limit | Albert Einstein |
1911 | Atomic Nucleus | ๐ฏ Nuclear model of atom; nuclear physics | Ernest Rutherford |
1913 | Bohr Model | ๐ Quantized atomic orbits; spectroscopy | Niels Bohr |
1915 | General Relativity | ๐ Gravity as curved spacetime; cosmology | Albert Einstein |
1925-27 | Quantum Mechanics | ๐ฒ Wave-particle duality; uncertainty principle | Heisenberg, Schrรถdinger, Bohr |
1927 | Big Bang Theory | ๐ฅ Origin and expansion of universe | Georges Lemaรฎtre |
1929 | Expanding Universe | ๐ญ Galaxies receding; cosmic expansion confirmed | Edwin Hubble |
1932 | Neutron | โช Nuclear structure; fission possibility | James Chadwick |
1932 | Antimatter | โโ Positron discovery; matter-antimatter symmetry | Carl David Anderson |
1938 | Nuclear Fission | โ๏ธ๐ฅ Nuclear power; atomic weapons | Hahn, Meitner, Strassmann |
1948 | Quantum Electrodynamics | ๐ Quantum field theory; most accurate theory | Feynman, Tomonaga, Schwinger |
1956 | Neutrino Detection | ๐ป Ghostly particles; solar processes | Cowan & Reines |
1964 | Quarks | ๐ด๐ต Building blocks of protons/neutrons | Gell-Mann & Zweig |
1965 | Cosmic Microwave Background | ๐ป Big Bang evidence; universe's baby picture | Penzias & Wilson |
1967 | Electroweak Unification | ๐ Two forces unified; Standard Model | Weinberg, Salam, Glashow |
1970-73 | Standard Model | ๐งฉ Complete theory of particles and forces | Various physicists |
1974 | Hawking Radiation | ๐ณ๏ธ Black holes evaporate; quantum gravity | Stephen Hawking |
1980 | Quantum Computing | ๐ป Quantum information processing proposed | Richard Feynman |
1995 | Bose-Einstein Condensate | โ๏ธ New state of matter; quantum effects visible | Ketterle, Cornell, Wieman |
1998 | Dark Energy | ๐ Accelerating universe expansion | Supernova teams |
2012 | Higgs Boson | ๐พ Origin of mass; Standard Model completed | CERN LHC teams |
2015 | Gravitational Waves | ๐ Spacetime ripples detected; new astronomy | LIGO collaboration |
2019 | Black Hole Image | ๐ธ First visual proof; event horizon confirmed | Event Horizon Telescope |
๐งฌ Medicine - Innovation Timelineโ
Year | Innovation | Features | Innovator |
---|---|---|---|
c.460-377 BCE | Hippocratic Medicine | โ๏ธ Systematic observation, Hippocratic Oath, clinical approach | Hippocrates |
1543 | Human Anatomy | ๐ Detailed anatomical study; foundation of modern anatomy | Andreas Vesalius |
1590s | Compound Microscope | ๐ฌ Magnification of specimens; enabled cellular discovery | Hans & Zacharias Janssen |
1628 | Blood Circulation | ๐ Discovery of circulatory system; foundation of cardiology | William Harvey |
1665 | Cell Discovery | ๐ฌ First observation of cells; basis of cell theory | Robert Hooke |
1683 | Bacteria Discovery | ๐ฆ First observation of microorganisms; microbiology foundation | Anton van Leeuwenhoek |
1796 | Vaccination | ๐ First vaccine using cowpox to prevent smallpox | Edward Jenner |
1816 | Stethoscope | ๐ฉบ First instrument for cardiac auscultation | Renรฉ Laennec |
1842 | Anesthesia | ๐ด First surgical anesthesia using ether; painless surgery | Crawford Long |
1846 | Public Anesthesia | ๐ฅ First public demonstration of surgical anesthesia | William Morton |
1847 | Antiseptic Surgery | ๐งผ Hand washing reduces puerperal fever deaths | Ignaz Semmelweis |
1859 | Evolution Theory | ๐งฌ Natural selection; foundation of modern biology | Charles Darwin |
1865 | Genetics Laws | ๐ฑ Laws of inheritance; foundation of genetics | Gregor Mendel |
1867 | Antiseptic Principle | ๐งฝ Carbolic acid antisepsis; reduced surgical infections | Joseph Lister |
1869 | Periodic Table | โ๏ธ Chemical element organization; basis of chemistry | Dmitri Mendeleev |
1882 | TB Bacillus Discovery | ๐ฌ Identification of tuberculosis pathogen | Robert Koch |
1895 | X-rays | โข๏ธ Medical imaging; first internal body visualization | Wilhelm Rรถntgen |
1897 | Electron Discovery | โก Fundamental particle discovery; physics foundation | J.J. Thomson |
1901 | Blood Types | ๐ฉธ ABO blood group system; safe blood transfusions | Karl Landsteiner |
1903 | Electrocardiograph | ๐ First ECG machine; heart electrical activity measurement | Willem Einthoven |
1905 | Special Relativity | ๐ Time-space relationship; modern physics foundation | Albert Einstein |
1928 | Penicillin | ๐ First antibiotic; revolutionized infection treatment | Alexander Fleming |
1929 | Insulin Treatment | ๐ Hormone therapy for diabetes; first protein drug | Frederick Banting, Charles Best |
1943 | Kidney Dialysis | ๐ฅ First artificial kidney machine; renal replacement therapy | Willem Kolff |
1944 | Heart Surgery | ๐ First successful cardiac procedure with bypass | Alfred Blalock, Helen Taussig |
1951 | HeLa Cells | ๐งช First immortal human cell line; cancer research tool | George Gey, Henrietta Lacks |
1953 | DNA Structure | ๐งฌ Double helix discovery; molecular biology foundation | James Watson, Francis Crick |
1954 | Kidney Transplant | ๐ซ First successful organ transplantation | Joseph Murray |
1955 | Polio Vaccine | ๐ First effective polio prevention; mass vaccination | Jonas Salk |
1967 | Heart Transplant | ๐ First human heart transplantation | Christiaan Barnard |
1972 | CT Scan | ๐ฅ๏ธ Computer tomography; 3D medical imaging | Godfrey Hounsfield |
1973 | Recombinant DNA | ๐งฌ Genetic engineering technology; biotechnology birth | Stanley Cohen, Herbert Boyer |
1975 | Monoclonal Antibodies | ๐ฌ Targeted therapy production; precision medicine | Cรฉsar Milstein, Georges Kรถhler |
1978 | IVF Birth | ๐ถ First test-tube baby; reproductive medicine | Robert Edwards, Patrick Steptoe |
1979 | MRI Imaging | ๐ง Magnetic resonance imaging; soft tissue visualization | Paul Lauterbur, Peter Mansfield |
1982 | Artificial Heart | ๐ค First artificial heart implant; mechanical organ | Robert Jarvik |
1985 | PCR Technology | ๐งฌ DNA amplification; molecular diagnostics revolution | Kary Mullis |
1990 | Gene Therapy | ๐งฌ First approved gene therapy for ADA deficiency | William French Anderson |
1996 | Cloning (Dolly) | ๐ First cloned mammal; reproductive technology | Ian Wilmut, Roslin Institute |
2001 | Human Genome Project | ๐งฌ Complete human DNA sequence; personalized medicine | International Human Genome Consortium |
2003 | Face Transplant | ๐ค First partial face transplantation | Jean-Michel Dubernard |
2006 | HPV Vaccine | ๐ First cancer prevention vaccine | Ian Frazer |
2007 | iPS Cells | ๐ Induced pluripotent stem cells; regenerative medicine | Shinya Yamanaka |
2010 | 3D Bioprinting | ๐จ๏ธ First bioprinted blood vessels; organ printing | Organovo |
2012 | CRISPR Gene Editing | โ๏ธ Precise DNA editing tool; genetic disease treatment | Jennifer Doudna, Emmanuelle Charpentier |
2013 | Cancer Therapy | ๐ก๏ธ Engineered immune cells; cancer immunotherapy | Carl June, University of Pennsylvania |
2018 | CRISPR Babies | ๐ถ First gene-edited human babies (controversial) | He Jiankui |
2020 | mRNA Vaccines | ๐ Rapid COVID-19 vaccine development; mRNA technology | BioNTech/Pfizer, Moderna |
2021 | AI Drug Discovery | ๐ค AI-designed drugs enter clinical trials; computational medicine | DeepMind, Multiple Pharma Companies |
2023 | Base Editing | ๐ฌ Precise single-letter DNA editing; next-gen gene therapy | David Liu, Broad Institute |